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Table 1 Background characteristics of the full economic evaluations

From: Are vaccination programmes delivered by lay health workers cost-effective? A systematic review

 

Deuson et al. [17]

San Sebastian et al. [18]

Weaver et al. [19]

Area studied

Philadelphia, USA

Low-Napo area in Napo province, covering 300 km of the Napo river

Seattle, USA

Timing of the study

October 1994 - February 1996

1993-1995

October- November 1996

Type of intervention

Promotion prior to a catch-up campaign1

Campaign

Promotion

Type of LHW/role of LHW

Staff of community-based organisation

CHWs*

Senior volunteers, i.e. older people

Training

Unstated

3-year training in preventive medicine, including immunisation, and curative activities

Received training about the pneumococcal and influenza vaccines and received technical support from the project coordinator.

Comparator(s)

(Implicitly) Doing nothing

Centrally planned strategy (District Hospital strategy) of immunizing children <1 year

(Implicitly) Doing nothing

Study type

CEA & CUA

CEA

CEA

Vaccines delivered

Hepatitis B

Routine childhood vaccines

Pneumococcal and influenza vaccines

Age group(s) targeted

2-13 year-olds

0-5 years-old

65 years +

Perspective(s)

Societal

Societal

Societal

$ per child vaccinated

Costs per child, per dose, and per completed series were $64, $119, and $537, respectively

$32 per FVC

Not stated

CE results

The cost per discounted year of life saved was $11,525 and the benefit-cost ratio was 4.44:1

CHW intervention dominated the District Hospital comparison

Intervention cost $35,486/QALY gained for the combined outreach initiative, $53,547/QALY for the pneumococcal vaccine and $130,908/QALY for the influenza vaccine. For seniors who had never received a vaccine, the combined outreach initiative cost $11,771/QALY gained, $38,030/QALY for the pneumococcal vaccine, and $22,431/QALY for the influenza vaccine.

Funded by

Centers for Disease Control (CDC), USA

Medicus Mundi Andalucia, Spain

CDC

  1. * Local indigenous organization started a PHC programme in 25 communities with training of CHWs. Each community has two CHWs with 3 year training in preventive medicine, including immunisation and curative activities. CHWs are literate and elected by their own community and receive no financial reward.
  2. 1 Catch-up campaign: targeted efforts to vaccinate individuals that did not receive the vaccine that they would otherwise have received through routine immunisation
  3. Campaign: targeted efforts of vaccinating a group of and/or a pre-determined number of individuals for vaccination