World Health Organization (WHO). Depression and Other Common Mental Disorders: Global Health Estimates. Geneva: World Health Organization; 2017. Licence: CC BY-NC-SA 3.0 IGO.2017.
Liu Q, He H, Yang J, Feng X, Zhao F, Lyu J. Changes in the global burden of depression from 1990 to 2017: Findings from the Global Burden of Disease study. J Psychiatr Res. 2020;126:134–40.
Masanotti GM, Paolucci S, Abbafati E, Serratore C, Caricato M. Sense of Coherence in Nurses: A Systematic Review. Int J Environ Res Public Health. 2020;17:6.
Gómez-Salgado J, Domínguez-Salas S, Romero-Martín M, Ortega-Moreno M, García-Iglesias JJ, Ruiz-Frutos C. Sense of coherence and psychological distress among healthcare workers during the COVID-19 pandemic in Spain. Sustainability. 2020;12(17):6855.
Burton A, Burgess C, Dean S, Koutsopoulou GZ, Hugh-Jones S. How effective are mindfulness-based interventions for reducing stress among healthcare professionals? A systematic review and meta-analysis. Stress Health. 2017;33(1):3–13.
Mata DA, Ramos MA, Bansal N, Khan R, Guille C, Di Angelantonio E, et al. Prevalence of depression and depressive symptoms among resident physicians: a systematic review and meta-analysis. JAMA. 2015;314(22):2373–83.
Maharaj S, Lees T, Lal S. Prevalence and risk factors of depression, anxiety, and stress in a cohort of australian nurses. Int J Environ Res Public Health. 2019;16(1):61.
de Oliveira GS, Jr., Chang R, Fitzgerald PC, Almeida MD, Castro-Alves LS, Ahmad S, et al. The Prevalence of Burnout and Depression and Their Association with Adherence to Safety and Practice Standards: A Survey of United States Anesthesiology Trainees. Anesthesia & Analgesia. 2013;117(1).
Melnyk BM, Orsolini L, Tan A, Arslanian-Engoren C, Melkus GDE, Dunbar-Jacob J, et al. A national study links nurses’ physical and mental health to medical errors and perceived worksite wellness. J Occup Environ Med. 2018;60(2):126–31.
Sen S, Kranzler HR, Krystal JH, Speller H, Chan G, Gelernter J, et al. A prospective cohort study investigating factors associated with depression during medical internship. Arch Gen Psychiatry. 2010;67(6):557–65.
Murphy JM, Laird NM, Monson RR, Sobol AM, Leighton AH. A 40-year perspective on the prevalence of depression: the Stirling County Study. Arch Gen Psychiatry. 2000;57(3):209–15.
Goldman ML, Shah RN, Bernstein CA. Depression and suicide among physician trainees: recommendations for a national response. JAMA Psychiat. 2015;72(5):411–2.
Nickell LA, Crighton EJ, Tracy CS, Al-Enazy H, Bolaji Y, Hanjrah S, et al. Psychosocial effects of SARS on hospital staff: survey of a large tertiary care institution. CMAJ. 2004;170(5):793–8.
Abolfotouh MA, AlQarni AA, Al-Ghamdi SM, Salam M, Al-Assiri MH, Balkhy HH. An assessment of the level of concern among hospital-based health-care workers regarding MERS outbreaks in Saudi Arabia. BMC Infect Dis. 2017;17(1):4.
Greenberg N, Docherty M, Gnanapragasam S, Wessely S. Managing mental health challenges faced by healthcare workers during covid-19 pandemic. BMJ. 2020;368:1211.
World Health Organization Regional Office for the Eastern Mediterranean. 2020. http://www.emro.who.int/index.html.
Rahman A. Mental disorders in the Eastern Mediterranean Region. Int J Public Health. 2018;63(1):9–10.
Sheikh JI, Cheema S, Chaabna K, Lowenfels AB, Mamtani R. Capacity building in health care professions within the Gulf cooperation council countries: paving the way forward. BMC Med Educ. 2019;19(1):83.
Shahri SS, Ghashghaee A, Behzadifar M, Bragazzi NL, Behzadifar M, Mousavinejad N, et al. Depression among Iranian nurses:a systematic review and meta-analysis. Med J Islam Repub Iran. 2017;31:130.
Ameri M, Nodoushan MRH, Shahbazzadeh A, Ahmadi MA. Depression and its main determinants among Iranian operating room personnel: a systematic review and meta-analysis. Int Clin Neurosci J. 2018;5(3):81–5.
Mohammadi M, Vaisi-Raygani AA, Jalali R, Salari N, Sabbaghchi M. Prevalence of depression in nurses working in iranian hospitals: a systematic review and meta-analysis. Int J Med Rev. 2020;7(1):32–8.
Fereidouni Z, Dehghan A, Najafi KM. The prevalence of depression among nurses in Iran: a systematic review and meta-analysis. Int J Med Rev. 2018;5(4):163–7.
Assadi SM, Nakhaei MR, Najafi F, Fazel S. Mental health in three generations of Iranian medical students and doctors. Soc Psychiatry Psychiatr Epidemiol. 2007;42(1):57–60.
Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al. Cochrane Handbook for Systematic Reviews of Interventions version 6.0 (updated July 2019. New York: Wiley; 2019.
Open Science Framework (OSF). OSF home 2020. https://osf.io/dashboard.
Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol. 2009;62(10):1006–12.
Beller EM, Glasziou PP, Altman DG, Hopewell S, Bastian H, Chalmers I, et al. PRISMA for Abstracts: reporting systematic reviews in journal and conference abstracts. PLoS Med. 2013;10(4):e1001419.
Chaabna K, Cheema S, Abraham A, Alrouh H, Mamtani R, Sheikh JI. Gray literature in systematic reviews on population health in the Middle East and North Africa: protocol of an overview of systematic reviews and evidence mapping. Syst Rev. 2018;7(1):94.
Chaabna K, Cheema S, Abraham A, Mamtani R. Strengthening literature search strategies for systematic reviews reporting population health in the Middle East and North Africa: A meta-research study. J Evid Based Med. 2020;13:192–8.
Chaabna K, Cheema S, Abraham A, Alrouh H, Lowenfels AB, Maisonneuve P, et al. Systematic overview of hepatitis C infection in the Middle East and North Africa. World J Gastroenterol. 2018;24(27):3038–54.
Chaabane S, Chaabna K, Abraham A, Mamtani R, Cheema S. Physical activity and sedentary behaviour in the Middle East and North Africa: an overview of systematic reviews and meta-analysis. Sci Rep. 2020;10:9363.
Chaabna K, Cheema S, Abraham A, Alrouh H, Mamtani R. Adult mortality trends in Qatar, 1989–2015: National population versus migrants. PLOS ONE. 2018;13(9):e0203996.
Cheema S, Maisonneuve P, Weber I, Fernandez-Luque L, Abraham A, Alrouh H, et al. Knowledge and perceptions about Zika virus in a Middle East country. BMC Infect Dis. 2017;17(1):524.
Cheema S, Maisonneuve P, Al-Thani MH, Al-Thani AAM, Abraham A, Al-Mannai GA, et al. Oral health behavior and factors associated with poor oral status in Qatar: results from a national health survey. J Public Health Dent. 2017;77(4):308–16.
Cheema S, Maisonneuve P, Zirie M, Jayyousi A, Alrouh H, Abraham A, et al. Risk factors for microvascular complications of diabetes in a high-risk middle east population. J Diabetes Res. 2018;2018:8964027.
Doraiswamy S, Jithesh A, Chaabane S, Abraham A, Chaabna K, Cheema S. Perinatal mental illness in the middle east and north africa region—a systematic overview. Int J Environ Res Public Health. 2020;17(15):5487.
Al Manhal. : About us 2021. https://www.almanhal.com/en/Page/About.
Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan—a web and mobile app for systematic reviews. Syst Rev. 2016;5(1):210.
Higgins JPT, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343:5928.
Institute of Medicine. Finding What Works in Health Care: Standards for Systematic Reviews. Eden J, Levit L, Berg A, Morton S, editors. Washington, DC: The National Academies Press; 2011. 340 p.
Daniel W. Biostatistics: A foundation for analysis in the health sciences. 7th ed. New York: John Wiley and Sons; 2000.
Joules N, Williams DM, Thompson AW. Depression in resident physicians: a systematic review. Open J Depr. 2014;3:12.
Rahmati F, Safari S, Hashemi B, Baratloo A, Khosravi Rad R. Prevalence of Depression and Personality Disorders in the Beginning and End of Emergency Medicine Residency Program; a Prospective Cross Sectional Study. Arch Acad Emerg Med. 2019;7(1):e5.
AlGhamdi BS, AlAtawi Y, AlShehri FS, Tayeb HO, Taleb HAA, Binsalman A. Psychological Distress during COVID-19 Curfews and Social Distancing in Saudi Arabia: A Cross-Sectional Study. Research Square [Pre-print]. 2020.
Badahdah A, Khamis F, Al Mahyijari N, Al Balushi M, Al Hatmi H, Al Salmi I, et al. The mental health of health care workers in Oman during the COVID-19 pandemic. Int J Soc Psychiatry. 2020:0020764020939596.
Jabeen Z, Rani A, Ahmed S, Ghaffar S, Kazmi TH, Wasimud D. Psychological impact of COVID-19 pandemic on health care workers: a cross sectional study. Biomedica. 2020;36:209–13.
Mehdi M, Waseem M, Rehm MH, Aziz N, Anjum S, Javid MA. Depression and anxiety in health care workers during COVID-19. Biomedica. 2020;36(S2):233–8.
Hassannia L, Taghizadeh F, Moosazadeh M, Zarghami M, Taghizadeh H, Fathi Dooki A, et al. Anxiety and Depression in Health Workers and General Population During COVID-19 Epidemic in IRAN: A Web-Based Cross-Sectional Study. MedRxiv [Pre-print]. 2020:2020.05.05.20089292.
Naser AY, Dahmash EZ, Al-Rousan R, Alwafi H, Alrawashdeh HM, Ghoul I, et al. Mental health status of the general population, healthcare professionals, and university students during 2019 coronavirus disease outbreak in Jordan: A cross-sectional study. MedRxiv. 2020;1:e01730.
Vahedian-Azimi A, Moayed MS, Rahimibashar F, Shojaei S, Ashtari S, Pourhoseingholi MA. Compare the severity of psychological distress among four groups of Iranian society in COVID-19 pandemic. Research Square [Pre-print]. 2020.
Kamimura A, Chen J, Nourian MM, Stoddard M, Sarray A. Stress, Depression and Job Satisfaction among Physicians in Iraq. Diversity Equality Health Care. 2018;15(2):71–6.
Al Ghailani B, Al Nuaimi MA, Al Mazrouei A, Al Shehhi E, Al Fahim M, Darwish E. Well-being of residents in training programs of Abu Dhabi health services Ibnosina. J Med Biomed Sci. 2018;10(3):77–82.
Ibrahim AY, Chamsi Basha A, Saquib J, Zaghloul MS, Al-Mazrou A, Saquib N. Sleep duration is associated with depressive symptoms among expatriate nurses. J Affect Disord. 2019;257:658–61.
Tajvar A, Saraji GN, Ghanbarnejad A, Omidi L, Hosseini SS, Abadi AS. Occupational stress and mental health among nurses in a medical intensive care unit of a general hospital in Bandar Abbas in 2013. Electron Physician. 2015;7(3):1108–13.
Albajjar MA, Bakarman MA. Prevalence and correlates of depression among male medical students and interns in Albaha University, Saudi Arabia. J Family Med Prim Care. 2019;8(6):1889–94.
Khalid S, Irfan U, Sheikh S, Faisal M. Frequency of stress and depression in female nurses working in a teaching hospital. Kust Med J. 2010;2(1):10–4.
Kashani P, Mirbaha S, Forouzanfar MM, Meschi F, Baratloo A. The Prevalence of Personality Disorders among Emergency Nurses Based on MMPI-2 Questionnaire; a Cross-sectional Study. Emerg (Tehran). 2017;5(1):e17.
Habibi R. The relationship between job stress and depression among nurses in Shahid Rajaie Hospitals and social security of Qazvin city in 2012. Edrak. 2014;9(35):45–50.
Almutairi I, Al-Rashdi M, Almutairi A. Prevalence and predictors of depression, anxiety and stress symptoms in paramedics at Saudi Red Crescent Authority. Saudi J Med Med Sci. 2020;8(2):105.
Nooli AEA, Asiri AAA, Asiri ANA, Alqarni MAH, Alhilali FMS, Alayafi MAM, et al. Prevalence of depression among medical interns in King Khalid University. Int J Med Res Prof. 2017;3(6):131–3.
El-Hamrawy L, Hegazy N, El-Halawany S. Prevalence of depressive symptoms among healthcare providers in Shibin El-Kom city in Menoufia governorate. Menoufia Med J. 2018;31(2):708–15.
Ross CA, Goldner EM. Stigma, negative attitudes and discrimination towards mental illness within the nursing profession: a review of the literature. J Psychiatr Ment Health Nurs. 2009;16(6):558–67.
Pocock L. Mental health issues in the Middle East: an overview. Middle East Journal of Psychiatry and Alzheimers. 2017;8(1):1–6.
Sewilam AM, Watson AMM, Kassem AM, Clifton S, McDonald MC, Lipski R, et al. Suggested avenues to reduce the stigma of mental illness in the Middle East. Int J Soc Psychiatry. 2014;61(2):111–20.
Blue B. National mental health survey of doctors and medical students. . Beyond Blue: the national depression initiative. 2013.
Elliot L, Tan J, Norris S. The mental health of doctors: a systematic literature review. Beyond Blue: The National Depression Initiative; 2010.
Khan A, Teoh KRH, Islam S, Hassard J. Psychosocial work characteristics, burnout, psychological morbidity symptoms and early retirement intentions: a cross-sectional study of NHS consultants in the UK. BMJ Open. 2018;8(7):e018720.
Berman R, Campbell M, Makin W, Todd C. Occupational stress in palliative medicine, medical oncology and clinical oncology specialist registrars. Clin Med (Lond). 2007;7(3):235–42.
Sakib N, Akter T, Zohra F, Bhuiyan AKMI, Mamun MA, Griffiths MD. Fear of COVID-19 and Depression: A Comparative Study Among the General Population and Healthcare Professionals During COVID-19 Pandemic Crisis in Bangladesh. International Journal of Mental Health and Addiction. 2021.
Tee ML, Tee CA, Anlacan JP, Aligam KJG, Reyes PWC, Kuruchittham V, et al. Psychological impact of COVID-19 pandemic in the Philippines. J Affect Disord. 2020;277:379–91.
Dave S, Parikh M, Vankar G, Valipay S. Depression, anxiety, and stress among resident doctors of a teaching hospital. Indian J Soc Psychiatry. 2018;34(2):163–71.
Raza A, Zainab H. Depression among doctors of selected public and private tertiary care hospitals in district Peshawar. J Rehman Med Inst. 2017;3(12):1–8.
Fawcett L. States and sovereignty in the Middle East: myths and realities. Int Aff. 2017;93(4):789–807.
Preti E, Di Mattei V, Perego G, Ferrari F, Mazzetti M, Taranto P, et al. The psychological impact of epidemic and pandemic outbreaks on healthcare workers: rapid review of the evidence. Curr Psychiatry Rep. 2020;22(8):43.
Rotenstein LS, Ramos MA, Torre M, Segal JB, Peluso MJ, Guille C, et al. Prevalence of depression, depressive symptoms, and suicidal ideation among medical students: a systematic review and meta-analysis. JAMA. 2016;316(21):2214–36.
Levy AB, Nahhas RW, Sampang S, Jacobs K, Weston C, Cerny-Suelzer C, et al. Characteristics associated with depression and suicidal thoughts among medical residents: results from the DEPRESS-Ohio Study. Acad Psychiatry. 2019;43(5):480–7.
Fahrenkopf AM, Sectish TC, Barger LK, Sharek PJ, Lewin D, Chiang VW, et al. Rates of medication errors among depressed and burnt out residents: prospective cohort study. BMJ. 2008;336(7642):488–91.
Stehman CR, Testo Z, Gershaw RS, Kellogg AR. Burnout, drop out, suicide: physician loss in emergency medicine. Part I West J Emerg Med. 2019;20(3):485–94.
Lim R, Aarsen KV, Gray S, Rang L, Fitzpatrick J, Fischer L. Emergency medicine physician burnout and wellness in Canada before COVID19: a national survey. CJEM. 2020;22(5):603–7.
Outhoff K. Depression in doctors: a bitter pill to swallow. S Afr Fam Pract. 2019;61(sup1):S11–4.
Bailey E, Robinson J, McGorry P. Depression and suicide among medical practitioners in Australia. Intern Med J. 2018;48(3):254–8.
Cleary M, Kornhaber R, Thapa DK, West S, Visentin D. The effectiveness of interventions to improve resilience among health professionals: a systematic review. Nurse Educ Today. 2018;71:247–63.
Guille C, Speller H, Laff R, Epperson CN, Sen S. Utilization and barriers to mental health services among depressed medical interns: a prospective multisite study. J Grad Med Educ. 2010;2(2):210–4.
Ruotsalainen JH, Verbeek JH, Mariné A, Serra C. Preventing occupational stress in healthcare workers. Cochrane Database Syst Rev. 2015;4:CD002892.
Ito M, Seo E, Ogawa R, Sanuki M, Maeno T, Maeno T. Can we predict future depression in residents before the start of clinical training? Med Educ. 2015;49(2):215–23.